According to statistics, approximately 18% to 30% of cell lines are cross contaminated or misidentified, and the use of this cell may lead to incorrect research conclusions, unrepeatable results, and catastrophic consequences of clinical cell therapy. Since 2009, NIH and ATCC have called on researchers to conduct STR identification of cells and begin establishing a cell STR database. Nowadays, cell STR identification has become the gold standard for identifying cell identity and cross contamination. Most authoritative journals also require authors to provide proof of cell STR identification when submitting their articles. In the production process of the biopharmaceutical industry, STR profiling has become an industry consensus for cell identification in cell bank assays.

20+1 human STR locus profiling by PCR-CE method, to identify whether it is a human cell and whether there is other human cell contamination. Database comparison to identify cell line/strains.

Project experience: The project has been in operation for ten years, with nearly 10,000 cases identified annually, serving more than 100 industrial customers, covering vaccines, bio-pharmaceuticals, cell therapy, gene editing, CRO/CDMO and cell banks. Quality assurance: The kit production and PCR standard laboratories are in line with ISO13485 and ISO17025 quality management certification; data processing and reporting are automated to avoid human errors to the greatest extent and ensure quality. Research and production strength: The first mouse and monkey Vero cell STR composite amplification system, closely following the domestic and foreign industry standards. Rigorous and realistic: treat large and small projects equally, take the initiative to re-examine contamination and doubtful results, and present data truthfully.

Receive a cell line into the laboratory After 10 passages After preparing a cell bank When in doubt

Cell pellet: cell number ≥ 5x10e5 gDNA：0.5μg